Monitoring and maintaining health - Non-communicable - OCR GatewayRisk factors and causal mechanisms

Scientists find links between diseases and their causes. The information is used to reduce the number of people with the disease by giving lifestyle advice or developing new ways to fight the disease.

Part of Biology (Single Science)Global challenges

Risk factors and causal mechanisms

Correlation

Scientists look for patterns in data and links between . If links or patterns are found this is called as one variable changes, so does the other.

Research has established links between cancer and various lifestyle factors, chemicals produced in the body, or that enter the human body, and chemicals in the environment.

Scientists have established several for risk factors.

Below is an example of how risk factors have been found. This has come from studies on smoking cigarettes and lung cancer.

Historically in the UK, a pattern can be seen between the number of people who smoke cigarettes and the number of smoking related deaths.

Graph showing estimated proportion of smokers from 2011 to 2019

As the number of people who smoke cigarettes has decreased over the years, the of smoking related deaths has decreased also. Note that there is a time lag, because cancer usually takes some years to develop.

There is a clear association, called a , between the variables. As one decreases, so does the other.

With cancer and other non-communicable diseases, scientists have found correlations. They then try to find the specific cause of the correlation.

Correlation and cause

If there is a correlation between a particular factor and an outcome, it does not mean that the factor necessarily causes the outcome. Scientists must look for a possible causal mechanism by which the factor could be the likely cause.

In the case of lung cancer, scientific analyses of cigarette smoke have shown that at least 70 of the chemicals present in smoke will cause cancer in laboratory animals. This establishes a causal link.

Learn more about risk factors for non communicable diseases with Dr Alex Lathbridge.

In this podcast, learn the key facts about risk factors for non communicable diseases. Listen to the full series on BBC Sounds.